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The prokinetic effects of erythromycin have been investigated in infants with dysmotility associated with prematurity, in low birth‐weight infants recovering from abdominal surgery, and in older children with a variety of other gastrointestinal disorders. Only one randomized placebo‐controlled trial …Request PDF on ResearchGate | Erythromycin as a prokinetic agent in infants and children | Erythromycin has been used as an antibiotic for more than four decades, but only in the last 10 years Clinical trials of erythromycin as a prokinetic agent in preterm neonates have reported conflicting results. Aim: To systematically review the efficacy and safety of erythromycin as a prokinetic agent in preterm neonates. Methods: Only randomised controlled trials in preterm neonates (gestation 37 weeks) were considered eligible for inclusion. The primary outcome was the time to reach FEFs of 150 ml/kg/day.that infants in the erythromycin group achieved full feeds significantly earlier than the placebo group.10 However, three other studies that used low-dose erythromycin failed to show any significant difference between erythromycin and placebo in the times to establish full feeds in preterm infants 32 weeks’ gestation with feeding intolerance.Erythromycin as a prokinetic agent in preterm neonates: a systematic review Patole S, Rao S, Doherty D CRD summary This review assessed the http://canadianpillsbuy.com cialis 5 mg generico vendita efficacy and safety of erythromycin as a prokinetic agent in pre-term cialis online fast delivery neonates. The authors concluded that differences between the studies made it difficult to draw any clear conclusions. The authors' conclusionsCostalos C, Gounaris A, Varhalama E, et al. Erythromycin as a prokinetic agent in preterm infants. J Pediatr Gastroenterol Nutr. 2002;34:23-25. 3. Costalos C, Gavrili V, Skouteri V, et al. The effect of low-dose erythromycin on whole gastrointestinal transit time of …PEDIATRIC PHARMACOTHERAPY A Monthly Newsletter for Health Care Professionals from the University of Virginia Children’s Hospital Volume 16 Number 4 April 2010. Erythromycin as a Gastrointestinal Prokinetic Agent in Infants.motility is a common problem in preterm infants. In the past decade, erythromycin has been used for its motilinomimet-ric effect to facilitate enteral feeding in preterm infants. Although earlier studies suggested that erythromycin is an effective prokinetic agent, recent randomized control trials (RCTs) reveal conflicting findings.Erythromycin is a macrolide antibiotic that acts as a prokinetic agent by acting on motilin receptors and inducing phase III activity of the migratory motor complex (MMC), propagating contents from the stomach to the small intestine. 79 Erythromycin has no effect on esophageal motility, but it has been selectively used in infants with feeding intolerance. The oral dose of erythromycin is 1 to 3 mg/kg three … Oct 12, 2006It seems that erythromycin, as a motilin agonist, is able to augment the appearance of MMCs in premature infants in a manner that is very dependent …common problems in preterm, very-low-birth-weight (VLBW) infants. This double-blind, randomized, pla-cebo-controlled study aimed to assess the effective-ness of “high-dose” oral erythromycin as a prokinetic agent in decreasing the incidence of PNAC. Two sec-ondary end points, including the time to achieve fullEvidence-based information on erythromycin prokinetic from hundreds of trustworthy sources for health and social care. Erythromycin as a prokinetic agent in preterm neonates: a systematic review var _gaq = _gaq. More: Erythromycin for the prevention and treatment of feeding intolerance in preterm infants.Prokinetic Drug Therapy in Children: A Review of Current Options Costalos C, Gounaris A, Varhalama E, Kokori F, Alexiou N, Kolovou E. Erythromycin as a prokinetic agent in preterm infants. Review article: Erythromycin as a prokinetic agent in infants and children.
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